RNA Pol II Ser7-P antibody [4E12]

Description
Rat monoclonal [4E12] to RNA Polymerase II, recognizes carboxyl-terminal domain (CTD) when phosphorylated at Serine 7.

Specificity
Mammals, yeast, drosophila

Applications
Western Blot: 1:10
ChIP: 500 μL/ChIP

Product Size Code Price Buy
Product RNA Pol II Ser7-P antibody [4E12] Size 1 mL Code 4e12-1 Price $ 115
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Product RNA Pol II Ser7-P antibody [4E12] Size 5 mL Code 4e12-5 Price $ 365
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Isotype
IgG1

Host species & clonality
Rat monoclonal

Form
Hybridoma supernatant

Size
1 mL; 5 mL

Preservative
0.09 % Sodium azide

RRID
AB_2631443

Storage instructions
Shipped on blue ice. Upon receipt store at 4°C. Stable for one year.

  • Chapman RD, Heidemann M, Albert TK, Mailhammer R, Flatley A, Meisterernst M, Kremmer E, Eick D.: Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7. Science, 2007 Dec 14;318(5857):1780-2. (PubMed)

About RNA polymerase II

RNA polymerase II (Pol II) catalyzes DNA-directed mRNA synthesis during the transcription of protein-coding genes. It is found in the nucleus of eukaryotic cells. Pol II is a 550 kDa complex and consists of 12 subunits.

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Only for research applications, not for diagnostic or therapeutic use!