Visualization of DNA damage
The PARP1-Chromobody® visualizes endogenous PARP1 in real time in live cells.
The PARP1-Chromobody comprises the anti-PARP1 VHH derived from alpaca heavy chain antibody genetically fused to TagRFP or TagGFP2.
Monitor recruitment of PARP1 to DNA damage in real time
Live cell imaging
PARP1 as biomarker of DNA damage after microirradiation
- Easily transfect your cells
- Use PARP1-Chromobody® as marker of DNA damage after microirradiation
- PARP1-Chromobody® does not affect cell viability
Poly (ADP-ribose) polymerase 1 (PARP1) is one of the most abundant proteins in the nucleus and is involved in many cellular processes like DNA repair, transcriptional regulation, and modulation of chromatin structure.
PARP1-Chromobody Plasmid (tagGFP)
PARP1-Chromobody Plasmid (tagRFP)
Only for research applications, not for diagnostic or therapeutic use!